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Adjuvanted-SARS-CoV-2 Spike Protein-Based Microparticulate Vaccine Delivered by Dissolving Microneedles Induces Humoral, Mucosal, and Cellular Immune Responses in Mice

COVID-19 continues to cause an increase in the number of cases and deaths worldwide. Due to the ever-mutating nature of the virus, frequent vaccination against COVID-19 is anticipated. Most of the approved SARS-CoV-2 vaccines are administered using the conventional intramuscular route, causing vacci...

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Detalles Bibliográficos
Autores principales: Patil, Smital, Vijayanand, Sharon, Menon, Ipshita, Gomes, Keegan Braz, Kale, Akanksha, Bagwe, Priyal, Yacoub, Shadi, Uddin, Mohammad N., D’Souza, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457992/
https://www.ncbi.nlm.nih.gov/pubmed/37631046
http://dx.doi.org/10.3390/ph16081131