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Neuroprotective Effects of Tryptanthrin-6-Oxime in a Rat Model of Transient Focal Cerebral Ischemia

The activation of c-Jun N-terminal kinase (JNK) plays an important role in stroke outcomes. Tryptanthrin-6-oxime (TRYP-Ox) is reported to have high affinity for JNK and anti-inflammatory activity and may be of interest as a promising neuroprotective agent. The aim of this study was to investigate th...

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Detalles Bibliográficos
Autores principales: Plotnikov, Mark B., Chernysheva, Galina A., Smol’yakova, Vera I., Aliev, Oleg I., Anishchenko, Anna M., Ulyakhina, Olga A., Trofimova, Eugene S., Ligacheva, Anastasia A., Anfinogenova, Nina D., Osipenko, Anton N., Kovrizhina, Anastasia R., Khlebnikov, Andrei I., Schepetkin, Igor A., Drozd, Anastasia G., Plotnikov, Evgenii V., Atochin, Dmitriy N., Quinn, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10457995/
https://www.ncbi.nlm.nih.gov/pubmed/37630972
http://dx.doi.org/10.3390/ph16081057