Substitution of Coxsackievirus A16 VP1 BC and EF Loop Altered the Protective Immune Responses in Chimera Enterovirus A71

Hand, foot and mouth disease (HFMD) is a childhood disease caused by enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16). Capsid loops are important epitopes for EV-A71 and CV-A16. Seven chimeric EV-A71 (ChiE71) involving VP1 BC (45.5% similarity), DE, EF, GH and HI loops, VP2 EF loop and VP3 G...

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Detalles Bibliográficos
Autores principales: Tan, Xiu Hui, Chong, Wei Lim, Lee, Vannajan Sanghiran, Abdullah, Syahril, Jasni, Kartini, Suarni, Saiful Qushairi, Perera, David, Sam, I-Ching, Chan, Yoke Fun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458053/
https://www.ncbi.nlm.nih.gov/pubmed/37631931
http://dx.doi.org/10.3390/vaccines11081363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458053/
https://www.ncbi.nlm.nih.gov/pubmed/37631931
http://dx.doi.org/10.3390/vaccines11081363

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