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Aloe-Emodin Overcomes Anti-Cancer Drug Resistance to Temozolomide and Prevents Colony Formation and Migration in Primary Human Glioblastoma Cell Lines NULU and ZAR

Glioblastoma, the most dangerous and aggressive type of CNS tumor, appears resistant to many chemotherapy drugs. In the patient-derived glioma cell lines NULU and ZAR, which exhibit drug-resistant phenotypes, we investigated the effect of combined AE (Aloe-emodin) and TMZ (temozolomide) and found a...

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Detalles Bibliográficos
Autores principales: Staffieri, Sabrina, Russo, Veronica, Oliva, Maria Antonietta, Alborghetti, Marika, Russo, Miriam, Arcella, Antonietta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458156/
https://www.ncbi.nlm.nih.gov/pubmed/37630276
http://dx.doi.org/10.3390/molecules28166024