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Deubiquitinase OTUD6A Regulates Innate Immune Response via Targeting UBC13

OTUD6A is a deubiquitinase that plays crucial roles in various human diseases. However, the precise regulatory mechanism of OTUD6A remains unclear. In this study, we found that OTUD6A significantly inhibited the production of type I interferon. Consistently, peritoneal macrophages and bone marrow-de...

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Detalles Bibliográficos
Autores principales: Li, Zhiwei, Li, Guanwen, Li, Yunfei, Luo, Yujie, Jiang, Yuhan, Zhang, Ziyu, Zhou, Ziyi, Liu, Shengde, Wu, Chen, You, Fuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458163/
https://www.ncbi.nlm.nih.gov/pubmed/37632103
http://dx.doi.org/10.3390/v15081761