The Mechanism of Anti-Tumor Activity of 6-Morpholino- and 6-Amino-9-Sulfonylpurine Derivatives on Human Leukemia Cells

The aim of this study was to explore the mechanism of antitumor effect of (E)-6-morpholino-9-(styrylsulfonyl)-9H-purine (6-Morpholino-SPD) and (E)-6-amino-9-(styrylsulfonyl)-9H-purine (6-Amino-SPD). The effects on apoptosis induction, mitochondrial potential, and accumulation of ROS in treated K562...

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Detalles Bibliográficos
Autores principales: Leventić, Marijana, Opačak-Bernardi, Teuta, Rastija, Vesna, Matić, Josipa, Pavlović Saftić, Dijana, Ban, Željka, Žinić, Biserka, Glavaš-Obrovac, Ljubica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458232/
https://www.ncbi.nlm.nih.gov/pubmed/37630388
http://dx.doi.org/10.3390/molecules28166136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458232/
https://www.ncbi.nlm.nih.gov/pubmed/37630388
http://dx.doi.org/10.3390/molecules28166136

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