Cargando…

The Mechanism of Anti-Tumor Activity of 6-Morpholino- and 6-Amino-9-Sulfonylpurine Derivatives on Human Leukemia Cells

The aim of this study was to explore the mechanism of antitumor effect of (E)-6-morpholino-9-(styrylsulfonyl)-9H-purine (6-Morpholino-SPD) and (E)-6-amino-9-(styrylsulfonyl)-9H-purine (6-Amino-SPD). The effects on apoptosis induction, mitochondrial potential, and accumulation of ROS in treated K562...

Descripción completa

Detalles Bibliográficos
Autores principales:	Leventić, Marijana, Opačak-Bernardi, Teuta, Rastija, Vesna, Matić, Josipa, Pavlović Saftić, Dijana, Ban, Željka, Žinić, Biserka, Glavaš-Obrovac, Ljubica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458232/ https://www.ncbi.nlm.nih.gov/pubmed/37630388 http://dx.doi.org/10.3390/molecules28166136

Ejemplares similares

Synthesis, Antiproliferative Evaluation and QSAR Analysis of Novel Halogen- and Amidino-Substituted Benzothiazoles and Benzimidazoles
por: Rep Kaulić, Valentina, et al.
Publicado: (2022)

Novel 7-Chloro-4-aminoquinoline-benzimidazole Hybrids as Inhibitors of Cancer Cells Growth: Synthesis, Antiproliferative Activity, in Silico ADME Predictions, and Docking
por: Krstulović, Luka, et al.
Publicado: (2023)

Flexibility and Preorganization of Fluorescent Nucleobase-Pyrene Conjugates Control DNA and RNA Recognition
por: Ban, Željka, et al.
Publicado: (2020)

Novel 1,2,3-Triazole-Containing Quinoline–Benzimidazole Hybrids: Synthesis, Antiproliferative Activity, In Silico ADME Predictions, and Docking
por: Krstulović, Luka, et al.
Publicado: (2023)

Nucleobase–Guanidiniocarbonyl-Pyrrole Conjugates as Novel Fluorimetric Sensors for Single Stranded RNA
por: Ban, Željka, et al.
Publicado: (2017)

Dipeptides Containing Pyrene and Modified Photochemically Reactive Tyrosine: Noncovalent and Covalent Binding to Polynucleotides
por: Sviben, Igor, et al.
Publicado: (2023)

INTERACTIONS AMONG INTERLEUKIN-6, C-REACTIVE PROTEIN AND INTERLEUKIN-6 (-174) G/C POLYMORPHISM IN THE PATHOGENESIS OF CROHN’S DISEASE AND ULCERATIVE COLITIS
por: Takač, Boris, et al.
Publicado: (2020)

The Nature of the (Oligo/Hetero)Arene Linker Connecting Two Triarylborane Cations Controls Fluorimetric and Circular Dichroism Sensing of Various ds-DNAs and ds-RNAs
por: Tumir, Lidija-Marija, et al.
Publicado: (2023)

miR-29a-3p/T-bet Regulatory Circuit Is Altered in T Cells of Patients With Hashimoto’s Thyroiditis
por: Tokić, Stana, et al.
Publicado: (2018)

The Impact of Physical Activity on Adolescent Idiopathic Scoliosis
por: Glavaš, Josipa, et al.
Publicado: (2023)

Characterization of the TCRβ repertoire of peripheral MR1-restricted MAIT cells in psoriasis vulgaris patients
por: Jirouš Drulak, Maja, et al.
Publicado: (2023)

HLA-A, -B, -C, -DRB1, -DQA1, and -DQB1 allele and haplotype frequencies defined by next generation sequencing in a population of East Croatia blood donors
por: Tokić, Stana, et al.
Publicado: (2020)

Transient receptor potential cation channel subfamily C member 6 participates in functional regulation of vascular smooth muscle cells
por: Matic, Ljubica
Publicado: (2020)

Management of Anesthesia and Perioperative Procedures in a Child with Glucose-6-Phosphate Dehydrogenase Deficiency
por: Cicvarić, Ana, et al.
Publicado: (2022)

Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium
por: Narczyk, Marta, et al.
Publicado: (2022)

The Expression of T Cell FOXP3 and T-Bet Is Upregulated in Severe but Not Euthyroid Hashimoto's Thyroiditis
por: Tokić, Stana, et al.
Publicado: (2016)

Differential Skewing of Circulating MR1-Restricted and γδ T Cells in Human Psoriasis Vulgaris
por: Plužarić, Vera, et al.
Publicado: (2020)

Novel pyrene-calix[4]arene derivatives as highly sensitive sensors for nucleotides, DNA and RNA
por: Nikšić-Franjić, Ivana, et al.
Publicado: (2023)

2,4,6-Trimethyl-1,3,5-tris(morpholinomethyl)benzene
por: Ma, Hong-Ji, et al.
Publicado: (2008)

Interference of DNAJB6/MRJ Isoform Switch by Morpholino Inhibits Replication of HIV-1 and RSV
por: Ko, Shih-Han, et al.
Publicado: (2018)

Guidelines for morpholino use in zebrafish
por: Stainier, Didier Y. R., et al.
Publicado: (2017)

The role of school medicine in the early detection and management of adolescent idiopathic scoliosis
por: Glavaš, Josipa, et al.
Publicado: (2022)

LIFESTYLE RISK FACTORS AND BONE MASS IN RECURRENT STONE-FORMING PATIENTS: A CROSS-SECTIONAL STUDY IN 144 SUBJECTS
por: Marić, Ivana, et al.
Publicado: (2019)

Nutraceuticals and Metastasis Development
por: Saftić Martinović, Lara, et al.
Publicado: (2020)

In Vitro Validation of Phosphorodiamidate Morpholino Oligomers
por: Aung-Htut, May T., et al.
Publicado: (2019)

Relevance of CYP2D6 Gene Variants in Population Genetic Differentiation
por: Stojanović Marković, Anita, et al.
Publicado: (2022)

Impact of the Histidine-Triazole and Tryptophan-Pyrene Exchange in the WHW Peptide: Cu(II) Binding, DNA/RNA Interactions and Bioactivity
por: Krošl, Ivona, et al.
Publicado: (2022)

The GSTO2 (rs156697) Polymorphism Modifies Diabetic Nephropathy Risk
por: Pavlovic, Dragana, et al.
Publicado: (2023)

AMOD: a morpholino oligonucleotide selection tool
por: Klee, Eric W., et al.
Publicado: (2005)

Lessons from morpholino-based screening in zebrafish
por: Bedell, Victoria M., et al.
Publicado: (2011)

Versatile Synthesis and Rational Design of Caged Morpholinos
por: Ouyang, Xiaohu, et al.
Publicado: (2009)

In vivo Electroporation of Morpholinos into the Adult Zebrafish Retina
por: Thummel, Ryan, et al.
Publicado: (2011)

N-Morpholino-Δ(8)-dihydroabietamide
por: Rao, Xiao-Ping
Publicado: (2010)

Polyphenol-Based Design of Functional Olive Leaf Infusions(§)
por: Peršurić, Željka, et al.
Publicado: (2019)

Novel Antiretroviral Structures from Marine Organisms
por: Wittine, Karlo, et al.
Publicado: (2019)

Pharmacologic Evaluation of Antidepressant Activity and Synthesis of 2-Morpholino-5-phenyl-6H-1,3,4-thiadiazine Hydrobromide
por: Sarapultsev, Alexey P., et al.
Publicado: (2016)

Antioxidant Activity, Stability in Aqueous Medium and Molecular Docking/Dynamics Study of 6-Amino- and N-Methyl-6-amino-L-ascorbic Acid
por: Saftić Martinović, Lara, et al.
Publicado: (2023)

Expression of Interleukin 6 signaling receptors in carotid atherosclerosis
por: Ziegler, Louise, et al.
Publicado: (2020)

N-[Morpholino(phenyl)methyl]benzamide
por: Muruganandam, L., et al.
Publicado: (2009)

4′-(Morpholinomethyl)biphenyl-2-carbonitrile
por: SiMa, Weiwei
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_ol906tkpurci6sel2hinjs809k