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Design and Synthesis of New Anthranyl Phenylhydrazides: Antileishmanial Activity and Structure–Activity Relationship

Leishmaniasis is a neglected tropical disease affecting millions of people worldwide. A centenary approach to antimonial-based drugs was first initiated with the synthesis of urea stibamine by Upendranath Brahmachari in 1922. The need for new drug development led to resistance toward antimoniates. N...

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Detalles Bibliográficos
Autores principales: do Carmo Maquiaveli, Claudia, da Silva, Edson Roberto, Hild de Jesus, Barbara, Oliveira Monteiro, Caio Eduardo, Rodrigues Navarro, Tiago, Pereira Branco, Luiz Octavio, Souza dos Santos, Isabela, Figueiredo Reis, Nanashara, Portugal, Arieli Bernardo, Mendes Wanderley, João Luiz, Borges Farias, André, Correia Romeiro, Nelilma, de Lima, Evanoel Crizanto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458276/
https://www.ncbi.nlm.nih.gov/pubmed/37631035
http://dx.doi.org/10.3390/ph16081120