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VP4/VP56/VP35 Virus-like Particles Effectively Protect Grass Carp (Ctenopharyngodon idella) against GCRV-II Infection
HIGHLIGHTS: 1. .. Three outer capsid proteins of GCRV-II self-assemble into VLPs in vitro. 2. .. VLPs vaccine have low toxicity and uniform particle size. 3. .. VLPs + astragalus polysaccharide improve protection and reduces tissue viral load. 4. .. VLPs vaccine induce immune response and regulate a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458301/ https://www.ncbi.nlm.nih.gov/pubmed/37631941 http://dx.doi.org/10.3390/vaccines11081373 |