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VP4/VP56/VP35 Virus-like Particles Effectively Protect Grass Carp (Ctenopharyngodon idella) against GCRV-II Infection

HIGHLIGHTS: 1. .. Three outer capsid proteins of GCRV-II self-assemble into VLPs in vitro. 2. .. VLPs vaccine have low toxicity and uniform particle size. 3. .. VLPs + astragalus polysaccharide improve protection and reduces tissue viral load. 4. .. VLPs vaccine induce immune response and regulate a...

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Detalles Bibliográficos
Autores principales: Tian, Qingqing, Huo, Xingchen, Liu, Qian, Yang, Chunrong, Zhang, Yongan, Su, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458301/
https://www.ncbi.nlm.nih.gov/pubmed/37631941
http://dx.doi.org/10.3390/vaccines11081373