A NRF2-induced secretory phenotype activates immune surveillance to remove irreparably damaged cells

While it is well established that the KEAP1-NRF2 pathway regulates the main inducible cellular response to oxidative stress, this cytoprotective function of NRF2 could become deleterious to the host if it confers survival onto irreparably damaged cells. In this regard, we have found that in diseased...

Descripción completa

Detalles Bibliográficos
Autores principales: Baird, Liam, Taguchi, Keiko, Zhang, Anqi, Takahashi, Yushi, Suzuki, Takafumi, Kensler, Thomas W., Yamamoto, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458321/
https://www.ncbi.nlm.nih.gov/pubmed/37597423
http://dx.doi.org/10.1016/j.redox.2023.102845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458321/
https://www.ncbi.nlm.nih.gov/pubmed/37597423
http://dx.doi.org/10.1016/j.redox.2023.102845

Ejemplares similares