The Insertion of an Evolutionary Lost Four-Amino-Acid Cytoplasmic Tail Peptide into a Syncytin-1 Vaccine Increases T- and B-Cell Responses in Mice

Human endogenous retrovirus type W (HERV-W) is expressed in various cancers. We previously developed an adenovirus-vectored cancer vaccine targeting HERV-W by encoding an assembled HERV-W group-specific antigen sequence and the HERV-W envelope sequence Syncytin-1. Syncytin-1 is constitutively fusoge...

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Detalles Bibliográficos
Autores principales: Skandorff, Isabella, Gille, Jasmin, Ragonnaud, Emeline, Andersson, Anne-Marie, Schrödel, Silke, Thirion, Christian, Wagner, Ralf, Holst, Peter Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458386/
https://www.ncbi.nlm.nih.gov/pubmed/37632028
http://dx.doi.org/10.3390/v15081686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458386/
https://www.ncbi.nlm.nih.gov/pubmed/37632028
http://dx.doi.org/10.3390/v15081686

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