Transferrin-Decorated PLGA Nanoparticles Loaded with an Organoselenium Compound as an Innovative Approach to Sensitize MDR Tumor Cells: An In Vitro Study Using 2D and 3D Cell Models

Multidrug resistance (MDR) is the main challenge in cancer treatment. In this sense, we designed transferrin (Tf)-conjugated PLGA nanoparticles (NPs) containing an organoselenium compound as an alternative to enhance the efficacy of cancer therapy and sensitize MDR tumor cells. Cytotoxicity studies...

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Detalles Bibliográficos
Autores principales: Macedo, Letícia Bueno, Nogueira-Librelotto, Daniele Rubert, Mathes, Daniela, Pieta, Taís Baldissera, Mainardi Pillat, Micheli, da Rosa, Raquel Mello, Rodrigues, Oscar Endrigo Dorneles, Vinardell, Maria Pilar, Rolim, Clarice Madalena Bueno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458402/
https://www.ncbi.nlm.nih.gov/pubmed/37630891
http://dx.doi.org/10.3390/nano13162306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458402/
https://www.ncbi.nlm.nih.gov/pubmed/37630891
http://dx.doi.org/10.3390/nano13162306

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