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Improved Process for the Synthesis of 3-(3-Trifluoromethylphenyl)propanal for More Sustainable Production of Cinacalcet HCl †

Cinacalcet (I), sold as hydrochloride salt, is a calcimimetic drug which has been approved for the treatment of secondary hyperparathyroidism in patients with chronic renal disease and for the treatment of hypercalcemia in patients with parathyroid carcinoma. Here, an improved method for the synthes...

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Detalles Bibliográficos
Autores principales: Rathod, Vikas Damu, Paganelli, Stefano, Kočevar, Marijan, Krivec, Marko, Piccolo, Oreste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458415/
https://www.ncbi.nlm.nih.gov/pubmed/37630295
http://dx.doi.org/10.3390/molecules28166042