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Characterization of Anticancer Effects of the Analogs of DJ4, a Novel Selective Inhibitor of ROCK and MRCK Kinases

The Rho associated coiled-coil containing protein kinase (ROCK1 and ROCK2) and myotonic dystrophy-related Cdc-42 binding kinases (MRCKα and MRCKβ) are critical regulators of cell proliferation and cell plasticity, a process intimately involved in cancer cell migration and invasion. Previously, we re...

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Detalles Bibliográficos
Autores principales: Kale, Vijay Pralhad, Hengst, Jeremy A., Sharma, Arati K., Golla, Upendarrao, Dovat, Sinisa, Amin, Shantu G., Yun, Jong K., Desai, Dhimant H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458458/
https://www.ncbi.nlm.nih.gov/pubmed/37630974
http://dx.doi.org/10.3390/ph16081060