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Polysarcosine-Functionalized mRNA Lipid Nanoparticles Tailored for Immunotherapy

Lipid nanoparticles (LNPs) have gained great attention as carriers for mRNA-based therapeutics, finding applications in various indications, extending beyond their recent use in vaccines for infectious diseases. However, many aspects of LNP structure and their effects on efficacy are not well charac...

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Detalles Bibliográficos
Autores principales: Wilhelmy, Christoph, Keil, Isabell Sofia, Uebbing, Lukas, Schroer, Martin A., Franke, Daniel, Nawroth, Thomas, Barz, Matthias, Sahin, Ugur, Haas, Heinrich, Diken, Mustafa, Langguth, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458461/
https://www.ncbi.nlm.nih.gov/pubmed/37631282
http://dx.doi.org/10.3390/pharmaceutics15082068