Cargando…
Polysarcosine-Functionalized mRNA Lipid Nanoparticles Tailored for Immunotherapy
Lipid nanoparticles (LNPs) have gained great attention as carriers for mRNA-based therapeutics, finding applications in various indications, extending beyond their recent use in vaccines for infectious diseases. However, many aspects of LNP structure and their effects on efficacy are not well charac...
Autores principales: | Wilhelmy, Christoph, Keil, Isabell Sofia, Uebbing, Lukas, Schroer, Martin A., Franke, Daniel, Nawroth, Thomas, Barz, Matthias, Sahin, Ugur, Haas, Heinrich, Diken, Mustafa, Langguth, Peter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458461/ https://www.ncbi.nlm.nih.gov/pubmed/37631282 http://dx.doi.org/10.3390/pharmaceutics15082068 |
Ejemplares similares
-
Efficient Shielding of Polyplexes Using Heterotelechelic Polysarcosines
por: Klein, Philipp Michael, et al.
Publicado: (2018) -
Hybrid Biopolymer and Lipid Nanoparticles with Improved Transfection Efficacy for mRNA
por: Siewert, Christian D., et al.
Publicado: (2020) -
Polysarcosine-Based Lipids: From Lipopolypeptoid Micelles to Stealth-Like Lipids in Langmuir Blodgett Monolayers
por: Weber, Benjamin, et al.
Publicado: (2016) -
Iodine-124 PET quantification of organ-specific delivery and expression of NIS-encoding RNA
por: Miederer, Matthias, et al.
Publicado: (2021) -
Monodisperse polysarcosine-based highly-loaded antibody-drug conjugates
por: Viricel, Warren, et al.
Publicado: (2019)