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Electrophysiological Assessment of Newly Synthesized 2,3-Benzodiazepine Derivatives for Inhibiting the AMPA Receptor Channel

Three major subtypes of ionotropic receptors regulate glutamatergic synaptic transmission, one of which is α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors (AMPARs). They are tetrameric, cation-permeable ionotropic glutamate receptors found across the brain. Abnormalities in AM...

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Detalles Bibliográficos
Autores principales: Qneibi, Mohammad, Jumaa, Hanan, Bdir, Sosana, Al-Maharik, Nawaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458471/
https://www.ncbi.nlm.nih.gov/pubmed/37630319
http://dx.doi.org/10.3390/molecules28166067