Use of Biolayer Interferometry to Identify Dominant Binding Epitopes of Influenza Hemagglutinin Protein of A(H1N1)pdm09 in the Antibody Response to 2010–2011 Influenza Seasonal Vaccine

The globular head domain of influenza virus surface protein hemagglutinin (HA1) is the major target of neutralizing antibodies elicited by vaccines. As little as one amino acid substitution in the HA1 can result in an antigenic drift of influenza viruses, indicating the dominance of some epitopes in...

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Detalles Bibliográficos
Autores principales: Guo, Zhu, Lu, Xiuhua, Carney, Paul J., Chang, Jessie, Tzeng, Wen-pin, York, Ian A., Levine, Min Z., Stevens, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458479/
https://www.ncbi.nlm.nih.gov/pubmed/37631875
http://dx.doi.org/10.3390/vaccines11081307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458479/
https://www.ncbi.nlm.nih.gov/pubmed/37631875
http://dx.doi.org/10.3390/vaccines11081307

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