Sustained Inhibition of VEGF and TNF-α Achieves Multi-Ocular Protection and Prevents Formation of Blood Vessels after Severe Ocular Trauma

Purpose: This study aimed to develop a clinically feasible and practical therapy for multi-ocular protection following ocular injury by using a thermosensitive drug delivery system (DDS) for sustained delivery of TNF-α and VEGF inhibitors to the eye. Methods: A thermosensitive, biodegradable hydroge...

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Detalles Bibliográficos
Autores principales: Zhou, Chengxin, Lei, Fengyang, Sharma, Jyoti, Hui, Pui-Chuen, Wolkow, Natalie, Dohlman, Claes H., Vavvas, Demetrios G., Chodosh, James, Paschalis, Eleftherios I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458495/
https://www.ncbi.nlm.nih.gov/pubmed/37631272
http://dx.doi.org/10.3390/pharmaceutics15082059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458495/
https://www.ncbi.nlm.nih.gov/pubmed/37631272
http://dx.doi.org/10.3390/pharmaceutics15082059

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