Novel Quinazoline Derivative Induces Differentiation of Keratinocytes and Enhances Skin Barrier Functions against Th2 Cytokine-Mediated Signaling

Atopic dermatitis (AD) is a common inflammatory skin disease characterized by pruritic lesions and skin barrier dysfunction. In this study, we evaluated the effect of a quinazoline derivative, SH-340, on TSLP expression and signaling in human primary keratinocytes. Our results demonstrated that SH-3...

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Detalles Bibliográficos
Autores principales: Park, Yukyung, Srigouri, Huddar, Kim, Dongwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458605/
https://www.ncbi.nlm.nih.gov/pubmed/37630370
http://dx.doi.org/10.3390/molecules28166119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458605/
https://www.ncbi.nlm.nih.gov/pubmed/37630370
http://dx.doi.org/10.3390/molecules28166119

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