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Metabotropic Glutamate Receptor Subtype 5 Positron-Emission-Tomography Radioligands as a Tool for Central Nervous System Drug Development: Between Progress and Setbacks
The metabotropic glutamate receptor subtype 5 (mGluR5) is a class C G-protein-coupled receptor (GPCR) that has been implicated in various neuronal processes and, consequently, in several neuropsychiatric or neurodevelopmental disorders. Over the past few decades, mGluR5 has become a major focus for...
Autores principales: | Dupont, Anne-Claire, Arlicot, Nicolas, Vercouillie, Johnny, Serrière, Sophie, Maia, Serge, Bonnet-Brilhault, Frédérique, Santiago-Ribeiro, Maria-Joao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458693/ https://www.ncbi.nlm.nih.gov/pubmed/37631042 http://dx.doi.org/10.3390/ph16081127 |
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