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Mannose-Functionalized Isoniazid-Loaded Nanostructured Lipid Carriers for Pulmonary Delivery: In Vitro Prospects and In Vivo Therapeutic Efficacy Assessment

Resistance to isoniazid (INH) is common and increases the possibility of acquiring multidrug-resistant tuberculosis. For this study, isoniazid-loaded nanostructured lipid carriers (INH-NLCs) were developed and effectively functionalized with mannose (Man) to enhance the residence time of the drug wi...

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Detalles Bibliográficos
Autores principales: Ahalwat, Shaveta, Bhatt, Dinesh Chandra, Rohilla, Surbhi, Jogpal, Vikas, Sharma, Kirti, Virmani, Tarun, Kumar, Girish, Alhalmi, Abdulsalam, Alqahtani, Ali S., Noman, Omar M., Almoiliqy, Marwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458796/
https://www.ncbi.nlm.nih.gov/pubmed/37631023
http://dx.doi.org/10.3390/ph16081108