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Enhancement of Bottle Gourd Oil Activity via Optimized Self-Dispersing Lipid Formulations (SDLFs) to Mitigate Isoproterenol-Evoked Cardiac Toxicity in Rats via Modulating BMP, MMP2, and miRNA-21 and miRNA-23a Genes’ Expression

Bottle gourd (BG) oil (family Cucurbitaceae) has several pharmacological activities including a reduction of the hazard of cardiovascular and atherosclerosis conditions. This work aimed to develop and optimize self-dispersing lipid formulations (SDLFs) of BG oil by applying a full 3(2) factorial des...

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Detalles Bibliográficos
Autores principales: El-Mancy, Shereen S., Boshra, Sylvia A., Elnahas, Osama S., Fayez, Sahar M., Sheta, Nermin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458851/
https://www.ncbi.nlm.nih.gov/pubmed/37630419
http://dx.doi.org/10.3390/molecules28166168