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Stem Cell Bioengineering with Bioportides: Inhibition of Planarian Head Regeneration with Peptide Mimetics of Eyes Absent Proteins

Djeya1 (RKLAFRYRRIKELYNSYR) is a very effective cell penetrating peptide (CPP) that mimics the α5 helix of the highly conserved Eya domain (ED) of eyes absent (Eya) proteins. The objective of this study was to bioengineer analogues of Djeya1 that, following effective translocation into planarian tis...

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Detalles Bibliográficos
Autores principales: Jones, Sarah, Matos, Bárbara, Dennison, Sarah, Fardilha, Margarida, Howl, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10458859/
https://www.ncbi.nlm.nih.gov/pubmed/37631231
http://dx.doi.org/10.3390/pharmaceutics15082018