Comparative Serum and Brain Pharmacokinetics of Quercetin after Oral and Nasal Administration to Rats as Lyophilized Complexes with β-Cyclodextrin Derivatives and Their Blends with Mannitol/Lecithin Microparticles

Quercetin (Que) is one of the most studied flavonoids with strong antioxidant properties ascribed to its ability to bind free radicals and inactivate them. However, the low solubility of the compound along with its inadequate absorption after oral administration limit its beneficial effects. Que’s c...

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Detalles Bibliográficos
Autores principales: Manta, Konstantina, Papakyriakopoulou, Paraskevi, Nikolidaki, Anna, Balafas, Evangelos, Kostomitsopoulos, Nikolaos, Banella, Sabrina, Colombo, Gaia, Valsami, Georgia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459069/
https://www.ncbi.nlm.nih.gov/pubmed/37631250
http://dx.doi.org/10.3390/pharmaceutics15082036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459069/
https://www.ncbi.nlm.nih.gov/pubmed/37631250
http://dx.doi.org/10.3390/pharmaceutics15082036

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