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The Immunogenicity and Safety of Mycobacterium tuberculosis-mosR-Based Double Deletion Strain in Mice

Mycobacterium tuberculosis (M. tuberculosis) remains a significant global health threat, accounting for ~1.7 million deaths annually. The efficacy of the current vaccine, M. bovis BCG, ranges from 0 to 80% in children and does not prevent adulthood tuberculosis. We explored the immune profile and sa...

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Detalles Bibliográficos
Autores principales: Hildebrand, Rachel E., Hansen, Chungyi, Kingstad-Bakke, Brock, Wu, Chia-Wei, Suresh, Marulasiddappa, Talaat, Adel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459135/
https://www.ncbi.nlm.nih.gov/pubmed/37630665
http://dx.doi.org/10.3390/microorganisms11082105