Exploring Species-Specificity in TLR4/MD-2 Inhibition with Amphiphilic Lipid A Mimicking Glycolipids

The Toll-like receptor 4 (TLR4)/myeloid differentiation factor 2 (MD-2) complex is a key receptor of the innate immune system and a major driver of inflammation that is responsible for the multifaceted defense response to Gram-negative infections. However, dysfunction in the tightly regulated mechan...

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Detalles Bibliográficos
Autores principales: Borio, Alessio, Holgado, Aurora, Passegger, Christina, Strobl, Herbert, Beyaert, Rudi, Heine, Holger, Zamyatina, Alla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459247/
https://www.ncbi.nlm.nih.gov/pubmed/37630200
http://dx.doi.org/10.3390/molecules28165948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459247/
https://www.ncbi.nlm.nih.gov/pubmed/37630200
http://dx.doi.org/10.3390/molecules28165948

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