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Exploring Species-Specificity in TLR4/MD-2 Inhibition with Amphiphilic Lipid A Mimicking Glycolipids

The Toll-like receptor 4 (TLR4)/myeloid differentiation factor 2 (MD-2) complex is a key receptor of the innate immune system and a major driver of inflammation that is responsible for the multifaceted defense response to Gram-negative infections. However, dysfunction in the tightly regulated mechan...

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Detalles Bibliográficos
Autores principales:	Borio, Alessio, Holgado, Aurora, Passegger, Christina, Strobl, Herbert, Beyaert, Rudi, Heine, Holger, Zamyatina, Alla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459247/ https://www.ncbi.nlm.nih.gov/pubmed/37630200 http://dx.doi.org/10.3390/molecules28165948

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