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Delivery of RNA to the Blood-Brain Barrier Endothelium Using Cationic Bicelles

Blood-brain barrier (BBB) dysfunction is prevalent in Alzheimer’s disease and other neurological disorders. Restoring normal BBB function through RNA therapy is a potential avenue for addressing cerebrovascular changes in these disorders that may lead to cognitive decline. Although lipid nanoparticl...

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Detalles Bibliográficos
Autores principales: Cheng, Joan, Wang, Lushan, Guttha, Vineetha, Haugstad, Greg, Kandimalla, Karunya K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459289/
https://www.ncbi.nlm.nih.gov/pubmed/37631300
http://dx.doi.org/10.3390/pharmaceutics15082086