Multilocus Genetic Profile Reflecting Low Dopaminergic Signaling Is Directly Associated with Obesity and Cardiometabolic Disorders Due to Antipsychotic Treatment

Treatment with second-generation antipsychotics (SGAs) can cause obesity and other cardiometabolic disorders linked to D2 receptor (DRD2) and to genotypes affecting dopaminergic (DA) activity, within reward circuits. We explored the relationship of cardiometabolic alterations with single genetic pol...

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Detalles Bibliográficos
Autores principales: Arrue, Aurora, Olivas, Olga, Erkoreka, Leire, Alvarez, Francisco Jose, Arnaiz, Ainara, Varela, Noemi, Bilbao, Ainhoa, Rodríguez, Jose-Julio, Moreno-Calle, María Teresa, Gordo, Estibaliz, Marín, Elena, Garcia-Cano, Javier, Saez, Estela, Gonzalez-Torres, Miguel Ángel, Zumárraga, Mercedes, Basterreche, Nieves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459305/
https://www.ncbi.nlm.nih.gov/pubmed/37631349
http://dx.doi.org/10.3390/pharmaceutics15082134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459305/
https://www.ncbi.nlm.nih.gov/pubmed/37631349
http://dx.doi.org/10.3390/pharmaceutics15082134

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