Inhibition of Protein Aggregation and Endoplasmic Reticulum Stress as a Targeted Therapy for α-Synucleinopathy

α-synuclein (α-syn) is an intrinsically disordered protein abundant in the central nervous system. Physiologically, the protein regulates vesicle trafficking and neurotransmitter release in the presynaptic terminals. Pathologies related to misfolding and aggregation of α-syn are referred to as α-syn...

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Detalles Bibliográficos
Autores principales: Siwecka, Natalia, Saramowicz, Kamil, Galita, Grzegorz, Rozpędek-Kamińska, Wioletta, Majsterek, Ireneusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459316/
https://www.ncbi.nlm.nih.gov/pubmed/37631265
http://dx.doi.org/10.3390/pharmaceutics15082051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459316/
https://www.ncbi.nlm.nih.gov/pubmed/37631265
http://dx.doi.org/10.3390/pharmaceutics15082051

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