Enhancing Oral Bioavailability and Brain Biodistribution of Perillyl Alcohol Using Nanostructured Lipid Carriers

Perillyl alcohol (POH), a bioactive monoterpenoid derived from limonene, shows promise as an antitumor agent for brain tumor treatment. However, its limited oral bioavailability and inadequate brain distribution hinder its efficacy. To address these challenges, this study developed nanostructured li...

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Detalles Bibliográficos
Autores principales: Peczek, Samila Horst, Tartari, Ana Paula Santos, Zittlau, Isabella Camargo, Diedrich, Camila, Machado, Christiane Schineider, Mainardes, Rubiana Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459396/
https://www.ncbi.nlm.nih.gov/pubmed/37630970
http://dx.doi.org/10.3390/ph16081055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459396/
https://www.ncbi.nlm.nih.gov/pubmed/37630970
http://dx.doi.org/10.3390/ph16081055

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