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Ancistrocladinium A Induces Apoptosis in Proteasome Inhibitor-Resistant Multiple Myeloma Cells: A Promising Therapeutic Agent Candidate

The N,C-coupled naphthylisoquinoline alkaloid ancistrocladinium A belongs to a novel class of natural products with potent antiprotozoal activity. Its effects on tumor cells, however, have not yet been explored. We demonstrate the antitumor activity of ancistrocladinium A in multiple myeloma (MM), a...

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Detalles Bibliográficos
Autores principales: Brünnert, Daniela, Seupel, Raina, Goyal, Pankaj, Bach, Matthias, Schraud, Heike, Kirner, Stefanie, Köster, Eva, Feineis, Doris, Bargou, Ralf C., Schlosser, Andreas, Bringmann, Gerhard, Chatterjee, Manik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459547/
https://www.ncbi.nlm.nih.gov/pubmed/37631095
http://dx.doi.org/10.3390/ph16081181