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Taste-Masked Flucloxacillin Powder Part 2: Formulation Optimisation Using the Mixture Design Approach and Storage Stability

Flucloxacillin is prescribed to treat skin infections but its highly bitter taste is poorly tolerated in children. This work describes the application of the D-optimal mixture experimental design to identify the optimal component ratio of flucloxacillin, Eudragit EPO and palmitic acid to prepare flu...

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Detalles Bibliográficos
Autores principales: Yoo, Okhee, Salman, Sam, von Ungern-Sternberg, Britta S., Lim, Lee Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459548/
https://www.ncbi.nlm.nih.gov/pubmed/37631094
http://dx.doi.org/10.3390/ph16081179