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A Novel Dual-Payload ADC for the Treatment of HER2+ Breast and Colon Cancer
Antibody-drug conjugates (ADCs) have demonstrated a great therapeutic potential against cancer due to their target specificity and cytotoxicity. To exert a maximum therapeutic effect on cancerous cells, we have conjugated two different payloads to different amino acids, cysteines (cys) and lysines (...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459570/ https://www.ncbi.nlm.nih.gov/pubmed/37631234 http://dx.doi.org/10.3390/pharmaceutics15082020 |