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A Novel Dual-Payload ADC for the Treatment of HER2+ Breast and Colon Cancer

Antibody-drug conjugates (ADCs) have demonstrated a great therapeutic potential against cancer due to their target specificity and cytotoxicity. To exert a maximum therapeutic effect on cancerous cells, we have conjugated two different payloads to different amino acids, cysteines (cys) and lysines (...

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Detalles Bibliográficos
Autores principales: Mckertish, Candice Maria, Kayser, Veysel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459570/
https://www.ncbi.nlm.nih.gov/pubmed/37631234
http://dx.doi.org/10.3390/pharmaceutics15082020

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