Neuroprotective Impact of Linagliptin against Cadmium-Induced Cognitive Impairment and Neuropathological Aberrations: Targeting SIRT1/Nrf2 Axis, Apoptosis, and Autophagy

Cadmium is an environmental contaminant associated with marked neurotoxicity and cognitive impairment. Linagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, has demonstrated promising neuroprotection against cerebral ischemia and diabetic dementia. However, there has been no study of its effect o...

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Detalles Bibliográficos
Autores principales: Arab, Hany H., Eid, Ahmed H., Alsufyani, Shuruq E., Ashour, Ahmed M., El-Sheikh, Azza A. K., Darwish, Hany W., Georgy, Gehan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459587/
https://www.ncbi.nlm.nih.gov/pubmed/37630980
http://dx.doi.org/10.3390/ph16081065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459587/
https://www.ncbi.nlm.nih.gov/pubmed/37630980
http://dx.doi.org/10.3390/ph16081065

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