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Neuroprotective Impact of Linagliptin against Cadmium-Induced Cognitive Impairment and Neuropathological Aberrations: Targeting SIRT1/Nrf2 Axis, Apoptosis, and Autophagy
Cadmium is an environmental contaminant associated with marked neurotoxicity and cognitive impairment. Linagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, has demonstrated promising neuroprotection against cerebral ischemia and diabetic dementia. However, there has been no study of its effect o...
Autores principales: | Arab, Hany H., Eid, Ahmed H., Alsufyani, Shuruq E., Ashour, Ahmed M., El-Sheikh, Azza A. K., Darwish, Hany W., Georgy, Gehan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459587/ https://www.ncbi.nlm.nih.gov/pubmed/37630980 http://dx.doi.org/10.3390/ph16081065 |
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