Toward Stability Enhancement of NTS(1)R-Targeted Radioligands: Structural Interventions on [(99m)Tc]Tc-DT1

The neurotensin subtype 1 receptor (NTS(1)R) is overexpressed in a number of human tumors, thereby representing a valid target for cancer theranostics with radiolabeled neurotensin (NT) analogs like [(99m)Tc]Tc-DT1 (DT1, N(4)-Gly(7)-NT(8-13)). Thus far, the fast degradation of intravenously injected...

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Detalles Bibliográficos
Autores principales: Kanellopoulos, Panagiotis, Nock, Berthold A., Krenning, Eric P., Maina, Theodosia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459693/
https://www.ncbi.nlm.nih.gov/pubmed/37631306
http://dx.doi.org/10.3390/pharmaceutics15082092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459693/
https://www.ncbi.nlm.nih.gov/pubmed/37631306
http://dx.doi.org/10.3390/pharmaceutics15082092

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