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Real-Time Monitoring of Lysosomal Membrane Permeabilization Using Acridine Orange

Loss of lysosomal membrane integrity results in leakage of lysosomal hydrolases to the cytosol which might harm cell function and induce cell death. Destabilization of lysosomes often precede apoptotic or necrotic cell death and occur during both physiological and pathological conditions. The weak b...

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Detalles Bibliográficos
Autores principales: Eriksson, Ida, Vainikka, Linda, Persson, Hans Lennart, Öllinger, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459729/
https://www.ncbi.nlm.nih.gov/pubmed/37623923
http://dx.doi.org/10.3390/mps6040072