Formulation and Evaluation of a Self-Microemulsifying Drug Delivery System of Raloxifene with Improved Solubility and Oral Bioavailability

Poor aqueous solubility and dissolution limit the oral bioavailability of Biopharmaceutics Classification System (BCS) class II drugs. In this study, we aimed to improve the aqueous solubility and oral bioavailability of raloxifene hydrochloride (RLX), a BCS class II drug, using a self-microemulsify...

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Detalles Bibliográficos
Autores principales: Ansari, Muhammad Mohsin, Vo, Dang-Khoa, Choi, Ho-Ik, Ryu, Jeong-Su, Bae, Yumi, Bukhari, Nadeem Irfan, Zeb, Alam, Kim, Jin-Ki, Maeng, Han-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459739/
https://www.ncbi.nlm.nih.gov/pubmed/37631288
http://dx.doi.org/10.3390/pharmaceutics15082073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459739/
https://www.ncbi.nlm.nih.gov/pubmed/37631288
http://dx.doi.org/10.3390/pharmaceutics15082073

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