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Formulation and Evaluation of a Self-Microemulsifying Drug Delivery System of Raloxifene with Improved Solubility and Oral Bioavailability
Poor aqueous solubility and dissolution limit the oral bioavailability of Biopharmaceutics Classification System (BCS) class II drugs. In this study, we aimed to improve the aqueous solubility and oral bioavailability of raloxifene hydrochloride (RLX), a BCS class II drug, using a self-microemulsify...
Autores principales: | Ansari, Muhammad Mohsin, Vo, Dang-Khoa, Choi, Ho-Ik, Ryu, Jeong-Su, Bae, Yumi, Bukhari, Nadeem Irfan, Zeb, Alam, Kim, Jin-Ki, Maeng, Han-Joo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459739/ https://www.ncbi.nlm.nih.gov/pubmed/37631288 http://dx.doi.org/10.3390/pharmaceutics15082073 |
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