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A Study of the Bisphosphonic Derivatives from the Pudovik Reaction of Dialkyl α-Oxophosphonates and >P(O)H Reagents: X-ray Structure and Bioactivity

New hydroxy-methylenebisphosphonic derivatives were prepared with different P-functions. The outcome of the reaction of α-oxophosphonates (YC(O)P(O)(OR)(2)) and dialkyl phosphites or diarylphosphine oxides depended on the Y substituent of the oxo-compound, the nature of the P-reagent and the amount...

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Detalles Bibliográficos
Autores principales: Szalai, Zsuzsanna, Tóth, Boldizsár, Szabó, Rita Oláhné, Bősze, Szilvia, Karaghiosoff, Konstantin, Czugler, Mátyás, Drahos, László, Keglevich, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459769/
https://www.ncbi.nlm.nih.gov/pubmed/37630289
http://dx.doi.org/10.3390/molecules28166037