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LC-MS/MS Evaluation of Pyrrolizidine Alkaloids Profile in Relation to Safety of Comfrey Roots and Leaves from Polish Sources

Comfrey (Symphytum officinale L.) has a long tradition of use in the treatment of musculoskeletal disorders. However, due to hepatotoxic pyrrolizidine alkaloids (PAs), the EMA restricts the use of comfrey root (CR) to external use only and for short periods of time. Recent studies indicate a low per...

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Detalles Bibliográficos
Autores principales: Kimel, Katarzyna, Godlewska, Sylwia, Gleńsk, Michał, Gobis, Katarzyna, Ośko, Justyna, Grembecka, Małgorzata, Krauze-Baranowska, Mirosława
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459857/
https://www.ncbi.nlm.nih.gov/pubmed/37630423
http://dx.doi.org/10.3390/molecules28166171