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Synthesis and Anticancer Evaluation of 4-Chloro-2-((5-aryl-1,3,4-oxadiazol-2-yl)amino)phenol Analogues: An Insight into Experimental and Theoretical Studies

We report herein the synthesis, docking studies and biological evaluation of a series of new 4-chloro-2-((5-aryl-1,3,4-oxadiazol-2-yl)amino)phenol analogues (6a-h). The new compounds were designed based on the oxadiazole-linked aryl core of tubulin inhibitors of IMC-038525 and IMC-094332, prepared i...

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Detalles Bibliográficos
Autores principales: Afzal, Obaid, Ali, Amena, Ali, Abuzer, Altamimi, Abdulmalik Saleh Alfawaz, Alossaimi, Manal A., Bakht, Md Afroz, Salahuddin, Alamri, Mubarak A., Ahsan, Md. Faiyaz, Ahsan, Mohamed Jawed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459877/
https://www.ncbi.nlm.nih.gov/pubmed/37630338
http://dx.doi.org/10.3390/molecules28166086