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Efficacy, Pharmacokinetics, and Toxicity Profiles of a Broad Anti-SARS-CoV-2 Neutralizing Antibody

We recently reported the isolation and characterization of an anti-SARS-CoV-2 antibody, called IgG-A7, that protects transgenic mice expressing the human angiotensin-converting enzyme 2 (hACE-2) from an infection with SARS-CoV-2 Wuhan. We show here that IgG-A7 protected 100% of the transgenic mice i...

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Detalles Bibliográficos
Autores principales: Godínez-Palma, Silvia, González-González, Edith, Ramírez-Villedas, Frida, Garzón-Guzmán, Circe, Vallejo-Castillo, Luis, Carballo-Uicab, Gregorio, Marcelín-Jiménez, Gabriel, Batista, Dany, Pérez-Tapia, Sonia M., Almagro, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459920/
https://www.ncbi.nlm.nih.gov/pubmed/37632075
http://dx.doi.org/10.3390/v15081733