Exploring the application of sildenafil for high-fat diet-induced erectile dysfunction based on interleukin-18-mediated NLRP3/Caspase-1 signaling pathway

BACKGROUND: Inflammation is a key risk factor for heart disease and has also been linked to erectile dysfunction (ED). Sildenafil is a phosphodiesterase type 5 inhibitor with a strong antioxidant effect. Interleukin (IL)-18 is a proinflammatory factor. Excessive production and release of IL-18 disru...

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Detalles Bibliográficos
Autores principales: Zhu, Bingbing, Niu, Yangjiu, Niu, Lipan, Zhang, Xijia, Liu, Fengxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460117/
https://www.ncbi.nlm.nih.gov/pubmed/37636019
http://dx.doi.org/10.1093/sexmed/qfad044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460117/
https://www.ncbi.nlm.nih.gov/pubmed/37636019
http://dx.doi.org/10.1093/sexmed/qfad044

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