Spotlight on GOT2 in Cancer Metabolism

GOT2 is at the nexus of several critical metabolic pathways in homeostatic cellular and dysregulated cancer metabolism. Despite this, recent work has emphasized the remarkable plasticity of cancer cells to employ compensatory pathways when GOT2 is inhibited. Here, we review the metabolic roles of GO...

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Detalles Bibliográficos
Autores principales: Kerk, Samuel A, Garcia-Bermudez, Javier, Birsoy, Kivanc, Sherman, Mara H, Shah, Yatrik M, Lyssiotis, Costas A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460182/
https://www.ncbi.nlm.nih.gov/pubmed/37635751
http://dx.doi.org/10.2147/OTT.S382161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460182/
https://www.ncbi.nlm.nih.gov/pubmed/37635751
http://dx.doi.org/10.2147/OTT.S382161

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