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Spotlight on GOT2 in Cancer Metabolism
GOT2 is at the nexus of several critical metabolic pathways in homeostatic cellular and dysregulated cancer metabolism. Despite this, recent work has emphasized the remarkable plasticity of cancer cells to employ compensatory pathways when GOT2 is inhibited. Here, we review the metabolic roles of GO...
Autores principales: | Kerk, Samuel A, Garcia-Bermudez, Javier, Birsoy, Kivanc, Sherman, Mara H, Shah, Yatrik M, Lyssiotis, Costas A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460182/ https://www.ncbi.nlm.nih.gov/pubmed/37635751 http://dx.doi.org/10.2147/OTT.S382161 |
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