Suppression of P2X7R by Local Treatment Alleviates Acute Gouty Inflammation

OBJECTIVE: Gout is the most common inflammatory arthritis associated with interleukin-1β (IL-1β) accumulation during exacerbation. In this study, we aimed to clarify whether potassium channel antagonists attenuate local inflammation in mice with monosodium urate (MSU)-induced gout. METHODS: We cultu...

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Detalles Bibliográficos
Autores principales: Zhao, Yang, Li, Zhiyuan, Chen, Ying, Li, Yushuang, Lu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460186/
https://www.ncbi.nlm.nih.gov/pubmed/37636273
http://dx.doi.org/10.2147/JIR.S421548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460186/
https://www.ncbi.nlm.nih.gov/pubmed/37636273
http://dx.doi.org/10.2147/JIR.S421548

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